2008 Boston Red Sox Schedule
| Date | Opponent | Time | Broadcast | Probable Pitcher | Opposing Pitcher | |
| Tue, 3/25 | at Athletics | 6:05a | ESPN2, MLB.TV | Matsuzaka (0-0) | Blanton (0-0) |  |
| Wed, 3/26 | at Athletics | 6:05a | ESPN2, MLB.TV | Lester (0-0) | Harden (0-0) | |
| Tue, 4/1 | at Athletics | 10:05p | MLB.TV | Blanton (0-0) | ||
| Wed, 4/2 | at Athletics | 3:35p | MLB.TV | Harden (0-0) | ||
| Fri, 4/4 | at Blue Jays | 7:15p | MLB.TV | |||
| Sat, 4/5 | at Blue Jays | 1:07p | MLB.TV | |||
| Sun, 4/6 | at Blue Jays | 1:07p | TBS, MLB.TV | |||
| Tue, 4/8 | Tigers | 2:05p | MLB.TV | | ||
| Wed, 4/9 | Tigers | 7:05p | MLB.TV | |||
| Thu, 4/10 | Tigers | 7:05p | MLB.TV | |||
| Fri, 4/11 | Yankees | 7:05p | MLB.TV | | ||
| Sat, 4/12 | Yankees | 3:55p | FOX, MLB.TV | | ||
| Sun, 4/13 | Yankees | 8:05p | ESPN, MLB.TV | | ||
| Mon, 4/14 | at Indians | 7:05p | ESPN, MLB.TV | |||
| Tue, 4/15 | at Indians | 7:05p | MLB.TV | |||
| Wed, 4/16 | at Yankees | 7:05p | MLB.TV | |||
| Thu, 4/17 | at Yankees | TBD | MLB.TV | |||
| Fri, 4/18 | Rangers | 7:05p | MLB.TV | |||
| Sat, 4/19 | Rangers | 7:05p | MLB.TV | |||
| Sun, 4/20 | Rangers | 1:35p | MLB.TV | |||
| Mon, 4/21 | Rangers | 11:05a | MLB.TV | |||
| Tue, 4/22 | Angels | 7:05p | MLB.TV | |||
| Wed, 4/23 | Angels | 7:05p | MLB.TV | |||
| Thu, 4/24 | Angels | 1:35p | MLB.TV | |||
| Fri, 4/25 | at Rays | 7:10p | MLB.TV | |||
| Sat, 4/26 | at Rays | 7:10p | MLB.TV | |||
| Sun, 4/27 | at Rays | 1:40p | MLB.TV | |||
| Tue, 4/29 | Blue Jays | 7:05p | MLB.TV | |||
| Wed, 4/30 | Blue Jays | 7:05p | MLB.TV | |||
| Thu, 5/1 | Blue Jays | 7:05p | MLB.TV | |||
| Fri, 5/2 | Rays | 7:05p | MLB.TV | |||
| Sat, 5/3 | Rays | 7:05p | MLB.TV | |||
| Sun, 5/4 | Rays | 1:35p | MLB.TV | |||
| Mon, 5/5 | at Tigers | 7:05p | ESPN, MLB.TV | |||
| Tue, 5/6 | at Tigers | 7:05p | MLB.TV | |||
| Wed, 5/7 | at Tigers | 7:05p | MLB.TV | |||
| Thu, 5/8 | at Tigers | 7:05p | MLB.TV | |||
| Fri, 5/9 | at Twins | 8:10p | MLB.TV | |||
| Sat, 5/10 | at Twins | 7:10p | MLB.TV | |||
| Sun, 5/11 | at Twins | 8:05p | ESPN, MLB.TV | |||
| Mon, 5/12 | at Twins | 7:05p | ESPN, MLB.TV | |||
| Tue, 5/13 | at Orioles | 7:05p | MLB.TV | |||
| Wed, 5/14 | at Orioles | 3:05p | MLB.TV | |||
| Fri, 5/16 | Brewers | 7:05p | MLB.TV | |||
| Sat, 5/17 | Brewers | 3:55p | FOX, MLB.TV | |||
| Sun, 5/18 | Brewers | 1:35p | TBS, MLB.TV | |||
| Mon, 5/19 | Royals | 7:05p | MLB.TV | |||
| Tue, 5/20 | Royals | 7:05p | MLB.TV | |||
| Wed, 5/21 | Royals | 7:05p | MLB.TV | |||
| Thu, 5/22 | Royals | 1:35p | MLB.TV | |||
| Fri, 5/23 | at Athletics | 10:05p | MLB.TV | |||
| Sat, 5/24 | at Athletics | 9:05p | MLB.TV | |||
| Sun, 5/25 | at Athletics | 4:05p | MLB.TV | |||
| Mon, 5/26 | at Mariners | 10:10p | MLB.TV | |||
| Tue, 5/27 | at Mariners | 10:10p | MLB.TV | |||
| Wed, 5/28 | at Mariners | 10:10p | MLB.TV | |||
| Fri, 5/30 | at Orioles | 7:05p | MLB.TV | |||
| Sat, 5/31 | at Orioles | 7:05p | MLB.TV | |||
| Sun, 6/1 | at Orioles | 1:35p | MLB.TV | |||
| Mon, 6/2 | at Orioles | 7:05p | MLB.TV | |||
| Tue, 6/3 | Rays | 7:05p | MLB.TV | |||
| Wed, 6/4 | Rays | 7:05p | MLB.TV | |||
| Thu, 6/5 | Rays | 7:05p | MLB.TV | |||
| Fri, 6/6 | Mariners | 7:05p | MLB.TV | |||
| Sat, 6/7 | Mariners | 3:55p | FOX, MLB.TV | |||
| Sun, 6/8 | Mariners | 1:35p | MLB.TV | |||
| Tue, 6/10 | Orioles | 7:05p | MLB.TV | |||
| Wed, 6/11 | Orioles | 7:05p | MLB.TV | |||
| Thu, 6/12 | Orioles | 7:05p | MLB.TV | |||
| Fri, 6/13 | at Reds | 7:10p | MLB.TV | |||
| Sat, 6/14 | at Reds | 3:55p | FOX, MLB.TV | |||
| Sun, 6/15 | at Reds | 1:15p | MLB.TV | |||
| Mon, 6/16 | at Phillies | 7:05p | ESPN, MLB.TV | |||
| Tue, 6/17 | at Phillies | 7:05p | MLB.TV | |||
| Wed, 6/18 | at Phillies | 1:05p | MLB.TV | |||
| Fri, 6/20 | Cardinals | 7:05p | MLB.TV | |||
| Sat, 6/21 | Cardinals | 3:55p | FOX, MLB.TV | |||
| Sun, 6/22 | Cardinals | 1:35p | MLB.TV | |||
| Mon, 6/23 | Diamondbacks | 7:05p | MLB.TV | |||
| Tue, 6/24 | Diamondbacks | 7:05p | MLB.TV | |||
| Wed, 6/25 | Diamondbacks | 7:05p | MLB.TV | |||
| Fri, 6/27 | at Astros | 8:05p | MLB.TV | |||
| Sat, 6/28 | at Astros | 7:05p | MLB.TV | |||
| Sun, 6/29 | at Astros | 2:05p | MLB.TV | |||
| Mon, 6/30 | at Rays | 7:10p | MLB.TV | |||
| Tue, 7/1 | at Rays | 7:10p | MLB.TV | |||
| Wed, 7/2 | at Rays | 7:10p | MLB.TV | |||
| Thu, 7/3 | at Yankees | 7:05p | MLB.TV | |||
| Fri, 7/4 | at Yankees | 1:05p | MLB.TV | |||
| Sat, 7/5 | at Yankees | 3:55p | FOX, MLB.TV | |||
| Sun, 7/6 | at Yankees | TBD | MLB.TV | |||
| Mon, 7/7 | Twins | 7:05p | ESPN, MLB.TV | |||
| Tue, 7/8 | Twins | 7:05p | MLB.TV | |||
| Wed, 7/9 | Twins | 1:05p | MLB.TV | |||
| Fri, 7/11 | Orioles | 7:05p | MLB.TV | |||
| Sat, 7/12 | Orioles | 7:05p | MLB.TV | |||
| Sun, 7/13 | Orioles | 1:35p | MLB.TV | |||
| Fri, 7/18 | at Angels | 10:05p | MLB.TV | |||
| Sat, 7/19 | at Angels | 3:55p | FOX, MLB.TV | |||
| Sun, 7/20 | at Angels | 6:00p | MLB.TV | |||
| Mon, 7/21 | at Mariners | 10:10p | MLB.TV | |||
| Tue, 7/22 | at Mariners | 10:10p | MLB.TV | |||
| Wed, 7/23 | at Mariners | 4:40p | MLB.TV | |||
| Fri, 7/25 | Yankees | 7:05p | MLB.TV | | ||
| Sat, 7/26 | Yankees | 3:55p | FOX, MLB.TV | | ||
| Sun, 7/27 | Yankees | 1:35p | MLB.TV | | ||
| Mon, 7/28 | Angels | 7:05p | ESPN, MLB.TV | |||
| Tue, 7/29 | Angels | 7:05p | MLB.TV | |||
| Wed, 7/30 | Angels | 7:05p | MLB.TV | |||
| Fri, 8/1 | Athletics | 7:05p | MLB.TV | |||
| Sat, 8/2 | Athletics | 7:05p | MLB.TV | |||
| Sun, 8/3 | Athletics | 1:35p | MLB.TV | |||
| Mon, 8/4 | at Royals | 8:10p | ESPN, MLB.TV | |||
| Tue, 8/5 | at Royals | 8:10p | MLB.TV | |||
| Wed, 8/6 | at Royals | 8:10p | MLB.TV | |||
| Fri, 8/8 | at White Sox | 8:11p | MLB.TV | |||
| Sat, 8/9 | at White Sox | 7:05p | MLB.TV | |||
| Sun, 8/10 | at White Sox | 2:05p | MLB.TV | |||
| Mon, 8/11 | at White Sox | 8:11p | MLB.TV | |||
| Tue, 8/12 | Rangers | 7:05p | MLB.TV | |||
| Wed, 8/13 | Rangers | 7:05p | MLB.TV | |||
| Thu, 8/14 | Rangers | 7:05p | MLB.TV | |||
| Fri, 8/15 | Blue Jays | 7:05p | MLB.TV | |||
| Sat, 8/16 | Blue Jays | 7:05p | MLB.TV | |||
| Sun, 8/17 | Blue Jays | 1:35p | MLB.TV | |||
| Mon, 8/18 | at Orioles | 7:05p | MLB.TV | |||
| Tue, 8/19 | at Orioles | 7:05p | MLB.TV | |||
| Wed, 8/20 | at Orioles | 7:05p | MLB.TV | |||
| Fri, 8/22 | at Blue Jays | 7:07p | MLB.TV | |||
| Sat, 8/23 | at Blue Jays | 1:07p | MLB.TV | |||
| Sun, 8/24 | at Blue Jays | 1:07p | MLB.TV | |||
| Tue, 8/26 | at Yankees | 7:05p | MLB.TV | |||
| Wed, 8/27 | at Yankees | 7:05p | MLB.TV | |||
| Thu, 8/28 | at Yankees | 1:05p | MLB.TV | |||
| Fri, 8/29 | White Sox | 7:05p | MLB.TV | |||
| Sat, 8/30 | White Sox | 7:05p | MLB.TV | |||
| Sun, 8/31 | White Sox | 1:35p | MLB.TV | |||
| Mon, 9/1 | Orioles | 7:05p | MLB.TV | |||
| Tue, 9/2 | Orioles | 7:05p | MLB.TV | |||
| Wed, 9/3 | Orioles | 1:35p | MLB.TV | |||
| Fri, 9/5 | at Rangers | 8:05p | MLB.TV | |||
| Sat, 9/6 | at Rangers | 8:05p | MLB.TV | |||
| Sun, 9/7 | at Rangers | 3:05p | MLB.TV | |||
| Mon, 9/8 | Rays | 7:05p | MLB.TV | |||
| Tue, 9/9 | Rays | 7:05p | MLB.TV | |||
| Wed, 9/10 | Rays | 7:05p | MLB.TV | |||
| Fri, 9/12 | Blue Jays | 7:05p | MLB.TV | |||
| Sat, 9/13 | Blue Jays | 7:05p | MLB.TV | |||
| Sun, 9/14 | Blue Jays | 1:35p | MLB.TV | |||
| Mon, 9/15 | at Rays | 7:10p | MLB.TV | |||
| Tue, 9/16 | at Rays | 7:10p | MLB.TV | |||
| Wed, 9/17 | at Rays | 7:10p | MLB.TV | |||
| Fri, 9/19 | at Blue Jays | 7:07p | MLB.TV | |||
| Sat, 9/20 | at Blue Jays | 1:07p | MLB.TV | |||
| Sun, 9/21 | at Blue Jays | 1:07p | MLB.TV | |||
| Mon, 9/22 | Indians | 7:05p | MLB.TV | |||
| Tue, 9/23 | Indians | 7:05p | MLB.TV | |||
| Wed, 9/24 | Indians | 7:05p | MLB.TV | |||
| Thu, 9/25 | Indians | 7:05p | MLB.TV | |||
| Fri, 9/26 | Yankees | 7:05p | ESPN, MLB.TV | | ||
| Sat, 9/27 | Yankees | 7:05p | MLB.TV | | ||
| Sun, 9/28 | Yankees | 1:35p | MLB.TV |
